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Randomised, sham-controlled, double-blind trial · 2007

Red and near-infrared LEDs on wrinkles: a sham-controlled split-face trial

Researchers in Seoul wanted to know whether red light, near-infrared light or both could soften facial wrinkles, and whether any change could be seen under the microscope as well as in photos.

Short answer. One of the more carefully designed early trials: blinded, sham-controlled and backed by tissue samples. It supports red and near-infrared light for fine wrinkles, at clinic doses.

By Peter Groff, data analyst and editor · Reviewed

Lee SY, Park KH, Choi JW, et al. J Photochem Photobiol B. 2007;88(1):51–67. PubMed 17566756 · DOI

What they did

Seventy-six people with facial wrinkles were split into four groups. Each group had one half of the face treated with either 830 nm near-infrared light, 633 nm red light, both wavelengths, or a sham light that looked like treatment but was not meant to work.

Sessions ran twice a week for four weeks, followed by three months of check-ups. Neither participants nor assessors knew which light was being used. The team measured wrinkles with skin-surface mapping (profilometry), tested elasticity, and took small skin samples to look at collagen and inflammation markers.

What they found

All three real-light groups showed measurable wrinkle reductions compared with their starting point, up to 36%, and elasticity increases of up to 19%. Skin samples showed more collagen and elastic fibres and more active fibroblasts, the cells that build collagen.

No side effects were reported. The authors concluded that 830 nm and 633 nm LED light are an effective approach to skin rejuvenation.

What it cannot tell you

The biggest changes are reported against each person’s own baseline. The abstract does not say how large the difference was against the sham group, which is the comparison that matters most.

The light came from clinic panels, not a home mask, so the dose per session may differ from what any consumer device delivers.

In short

One of the more carefully designed early trials: blinded, sham-controlled and backed by tissue samples. It supports red and near-infrared light for fine wrinkles, at clinic doses.

Masks with these wavelengths

Eight of the 10 masks in the comparison list a wavelength in every band used here (red near 633 nm and near-infrared near 830 nm). They are examples, listed alphabetically, each with our specification page and the manufacturer’s own product page. They are not recommendations, and the links carry no affiliate parameters.

These masks list one of the bands, but not all:

Matching a wavelength is not the same as matching the study. Dose, irradiance, session length and schedule also differ, and a mask’s reported output is not independently measured. See how dose works and home vs clinic doses.

This is a plain-English summary of the published abstract, written by LED Translated. It is not medical advice, and it does not mean any mask reproduces this study’s results. Read the original record on PubMed, and talk to a qualified clinician about your skin.