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Systematic review of randomised controlled trials · 2018

LEDs in dermatology: what 31 randomised trials add up to

Instead of one experiment, this review collected every suitable randomised trial of LED light in dermatology available in 2017 and graded how strong the evidence was for each use.

Short answer. The clearest overall picture: acne and wound healing have the strongest LED evidence. Anti-ageing results are promising but rest on weaker trials.

By Peter Groff, data analyst and editor · Reviewed

Jagdeo J, Austin E, Mamalis A, et al. Lasers Surg Med. 2018;50(6):613–28. PubMed 29356026 · DOI

What they did

The authors systematically searched the published literature, included 31 randomised controlled trials, and assigned a grade of recommendation to each skin condition.

What they found

Acne, cold sores and shingles (herpes simplex and zoster), and acute wound healing received grade B, meaning moderately strong evidence. Other uses, including skin rejuvenation, received grade C or D.

Common weaknesses were small trials (often under 20 people), missing blinding, no sham light and inconsistent treatment settings. Given few side effects, low cost and encouraging results, the authors still recommended LEDs in clinical practice and called for more research.

What it cannot tell you

The review is from 2018. Several newer trials, including some described on this site, have been published since.

In short

The clearest overall picture: acne and wound healing have the strongest LED evidence. Anti-ageing results are promising but rest on weaker trials.

Masks with these wavelengths

Four of the 10 masks in the comparison list a wavelength in every band used here (blue near 415 nm and red, 620–670 nm). They are examples, listed alphabetically, each with our specification page and the manufacturer’s own product page. They are not recommendations, and the links carry no affiliate parameters.

These masks list one of the bands, but not all:

Matching a wavelength is not the same as matching the study. Dose, irradiance, session length and schedule also differ, and a mask’s reported output is not independently measured. See how dose works and home vs clinic doses.

This is a plain-English summary of the published abstract, written by LED Translated. It is not medical advice, and it does not mean any mask reproduces this study’s results. Read the original record on PubMed, and talk to a qualified clinician about your skin.